I am not familiar with Creo Schematic but the output in DWG is similar to DXF. If the export options exist, just output the file and see what they look like generically using one of many online tools. One thing I know that often fails is clean annotation. Often, text has no format option in the export so it always comes across as some substitution of TTF with width ratios of 1 and varying text origin. If you have an option to convert annotation to curves, then the receiving party cannot use the annotation other than visual reference (like a plot file).
Speaking of plot files, exporting as a postscript file is most generic and non-intelligent. This is easily converted back to DWG/DXF.
Whenever I have to do this for a client, it is a game of hit and miss. I would say start with the highest level of compatibility and look through the options to understand what you can vary. For schematics, this should be fairly straight forward.